interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF NUCLEOSOME COMPLEX WITH HUMAN TESTIS-SPECIFIC HISTONE VARIANTS, TH2A
(HISTONE H2A TYPE 1-A)
referenceKumarevel et al. 'Biophys. 221 41 2017
sourceHOMO SAPIENS
experimentX-ray (resolution=2.82, R-factor=0.214)
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes5gsu_ABCDEFGH 5gt0_ABCDEFGH
redundant complexes5gsu_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --RG----                               +8txv_G    
                     +-------------------1 
  --RG----           !                   +8ox0_C    
                     !  
  --RT----           !                    +8u14_G    
                 +--11                  +-2 
  --RA----       !   !        +---------5 +1zla_C    
                 !   !        !         ! 
  --RA--RA       !   !    +---7         +6a5l_g    
                 !   !    !   ! 
  --RG----       !   +----8   +----------8jla_C    
                 !        ! 
  --RT----     -12        !              +8smw_G    
                 !        +--------------3 
  --RG----       !                       +5x0y_G    
                 !  
  --RG--RG       !                +------8kcb_A    
                 !     +----------6 
  ----RA--       !     !          +------6g0l_D    
                 +----10  
  --RA----             !                 +7xsx_a    
                       !  +--------------4 
  --RT----             +--9              +8grq_A    
                          ! 
  LCRT----                +--------------8hr1_E    
               

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updated Sun Aug 3 09:11:19 2025