5hp4_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE BACTERIOHAGE T5 D15 FLAP ENDONUCLEASE (D155K) PSEUDO-ENZYME-PRODUCT COMPLEX WITH DNA AND METAL IONS (EXODEOXYRIBONUCLEASE)
reference	Sedelnikova et al. Nat.Struct.Mol.Biol. 23 640 2016
source	ESCHERICHIA PHAGE T5
experiment	X-ray (resolution=1.86, R-factor=0.160)
structural superfamily	PIN domain-like;5' to 3' exonuclease, C-terminal subdomain;
multimeric complexes	5hnk_AB
redundant complexes	5hnk_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5hp4_A interface=13,14,16,17,18,19,20,35,39,70,75,77,78,81,148,150,151,153,183, rnlmivdgtnlgFRfKHNNSkkpfassyvstiqsLaksYsarttivlgdkgksvfrlehlpeykgnrdeKyaqrTeEEkaLdeqffeylkdafelckttfptftirgveaddmaayivklighlydhvwlistdgkwdtlltdkvsrFsFTtRreyhlrdmyehhnvddveqfislkaimgdLgdnirgvegigakrgyniirefgnvldiidqlplpgkqkyiqnlnaseellfrnlilvdlptycvdaiaavgqdvldkftkdileiaeq
interface signature	FRKHNNSLYKTEELFFTRL

Estimated binding specificities ?

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# IC=5.416 IC/col=0.602 n_of_columns=9

specificity:

A |  38  21  24  24   0  21   0  96   0
C |  19  21  24  24   0  33  96   0   0
G |  19  23  24  24  96  21   0   0   0
T |  20  31  24  24   0  21   0   0  96

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------FCRT--KCHANGNASA----LT------KCTGEGEGLGFTFC----RTLA   L               +------5hp4_A    
                                                                          +--1 
  ------------------------------------------------------SG       +--------2  +------3zdb_A    
                                                                 !        ! 
  IGSTTGLTVA------------NCKAKANAKASA--------------MAHT----     --3        +---------2ihn_A    
                                                                 ! 
  ----------AG--------------------------------------------       +------------------5k97_A

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updated Fri Sep 13 19:45:26 2024