5j2p_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA THAT HAS INCORPORATED EFDA-MP AT THE P-(POST-TRANSLOCATION) SITE AND A SECOND EFDA-MP AT THE N-(PRE-TRANSLOCATION) SITE
reference	Sarafianos et al. Proc.Natl.Acad.Sci.USA 113 9274 2016
experiment	X-ray (resolution=2.53, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5j2p_A interface=94,183,265,356,448,475, pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqYmddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnrgrqkvvtltdttnQktelqaiylalqdsglevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvdklvsagirk > 5j2p_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdiphpaglkkkKsvtvldvgdayfsvpldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdLeigqhrtkieelrqhllrwglelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkaltevIplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwGktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYNRRQ/KLIG

Estimated binding specificities ?

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# IC=3.184 IC/col=0.199 n_of_columns=16

specificity:

A |  13   0  13  24  24  24  24  24  24  24  24  24  24  24  24   0
C |  13   0  57  24  24  24  24  24  24  24  24  24  24  24  24  96
G |  57   0  13  24  24  24  24  24  24  24  24  24  24  24  24   0
T |  13  96  13  24  24  24  24  24  24  24  24  24  24  24  24   0

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updated Mon Jan 5 18:39:02 2026