interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DTMPNPP OPPOSITE O6-METHYL-2'-DEOXYGUANOSINE
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 291 24304 2016
sourceHomo sapiens
experimentX-ray (resolution=1.94, R-factor=0.161)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSLRF

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |  13  24  54   0   0
C |  16  24  13  96   0
G |  13  24  16   0  96
T |  54  24  13   0   0
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updated Thu Sep 12 21:44:19 2024