interface graph thumbnail
legend  pdf

structure nameHUMAN CTCF ZNF3-7 AND METHYLATED DNA COMPLEX
(Transcriptional repressor CTCF)
referenceHashimoto et al. 'Mol. 66 711 2017
sourceHomo sapiens
experimentX-ray (resolution=2.19, R-factor=0.220)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex5kkq_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYEKRDYKRQTRSDV

Estimated binding specificities ?

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# IC=15.667 IC/col=1.119 n_of_columns=14 specificity:   
A |  75   9   0  78   0   0   0   0   0   0   0   6   0   0
C |   6   6  96   6  96  96  96  96  96   0   0  78   7   0
G |   9  75   0   6   0   0   0   0   0   0  96   6   0  96
T |   6   6   0   6   0   0   0   0   0  96   0   6  89   0
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updated Thu Sep 12 21:59:59 2024