interface graph thumbnail
legend  pdf

structure nameHUMAN CTCF ZNF3-7 AND METHYLATED DNA COMPLEX
(Transcriptional repressor CTCF)
referenceHashimoto et al. 'Mol. 66 711 2017
sourceHomo sapiens
experimentX-ray (resolution=2.19, R-factor=0.220)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYEKRDYKRQTRSDV

Estimated binding specificities ?

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# IC=15.573 IC/col=1.112 n_of_columns=14 specificity:   
A |   0  89   9   0  96   0   0   0   0   0   6   0   6   9
C |  96   1   6  96   0   0   0   0   0   0   6   0  75   6
G |   0   6  75   0   0  96  96  96  96  96   6  96   9   6
T |   0   0   6   0   0   0   0   0   0   0  78   0   6  75
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updated Tue Dec 17 02:29:15 2024