interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THYMINE DNA GLYCOSYLASE BOUND TO SUBSTRATE ANALOG 2'-F-5- FORMYL-DC
(GT mismatch-specific thymine DNA glycosylase)
referencePozharski et al. Biochemistry 55 6205 2016
sourceHomo sapiens
experimentX-ray (resolution=2.20, R-factor=0.182)
structural superfamilyUracil-DNA glycosylase-like;
sequence familyUracil DNA glycosylase superfamily;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSKKARCAQ

Estimated binding specificities ?

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# IC=3.143 IC/col=0.786 n_of_columns=4 specificity:   
A |  81   0   3  49
C |   4   0   3  17
G |   7  96   5  15
T |   4   0  85  15
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updated Tue Dec 17 02:29:36 2024