interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HHV-4 EBNA1 DNA BINDING DOMAIN (PATIENT-DERIVED, NASOPHARYNGEAL CARCINOMA) BOUND TO DNA
referenceLieberman et al. Oncotarget 8 7248 2017
sourceHuman herpesvirus 4 (strain B95-8) / Human herpesvirus 4 (strain B95-8) / Human herpesvirus 4 (strain B95-8) / Human herpesvirus 4 (strain B95-8)
experimentX-ray (resolution=2.35, R-factor=?)
structural superfamilyViral DNA-binding domain;
reference complex7u1t_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureWFRKFKTYNR/KWFKKTYNR

Estimated binding specificities ?

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# IC=14.541 IC/col=0.808 n_of_columns=18 specificity:   
A |   0   0   0   2  88  10   4  24  24  24  24   2  12   0  96   0   0   4
C |   2   0   0   7   2  12  88  24  24  24  24   2  69   2   0   2  96  88
G |  90  96  96   2   4  64   2  24  24  24  24  90  10   2   0   1   0   2
T |   4   0   0  85   2  10   2  24  24  24  24   2   5  92   0  93   0   2
scan!

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updated Mon Jan 5 22:01:05 2026