structure name | ENGINEERED VARIANT OF I-ONUI MEGANUCLEASE TARGETING THE HIV CCR5 GENE; HARBORS 43 POINT MUTATIONS RELATIVE TO WILD-TYPE I-ONUI (I-ONUI_E-HCCR5) |
reference | Hallinan et al. 'to ? ? ? |
source | SYNTHETIC CONSTRUCT |
experiment | X-ray (resolution=3.11, R-factor=0.226) |
structural superfamily | Homing endonucleases; |
sequence family | LAGLIDADG endonuclease; |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | SMRRYSETRTRWTYHYRRIQKMHTK |
Estimated binding specificities ?
readout + contact |
A | 6 0 24 0 0 89 0 0 96 24 24 24 16 24 1 0 0 0 6 0 C | 61 0 24 96 96 0 0 0 0 24 24 24 61 24 6 0 0 0 75 96 G | 16 0 24 0 0 0 96 96 0 24 24 24 13 24 0 0 96 96 6 0 T | 13 96 24 0 0 7 0 0 0 24 24 24 6 24 89 96 0 0 9 0scan! |
Dendrogram of similar interfaces ?
matrix formathome
updated Tue Dec 19 11:19:53 2023