5txo_AB : 3D-footprint complex

structure name	STRUCTURE OF Q151M COMPLEX (A62V, V75I, F77L, F116Y, Q151M) MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP
reference	Martinez et al.
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5txo_A interface=96,117,159,185,186,358,450,477, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfvikkkdstkwrklidlrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYysvpldedfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnQktelqaiylalqdsglevnivtnsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 5txo_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpLdedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkilepfkkqnpdiviyqymddlYVgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqKittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYPYMRRQ/GLSYVK

Estimated binding specificities ?

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# IC=4.723 IC/col=0.278 n_of_columns=17

specificity:

A |   0   0  19  24  24  24  24  24  24  24  24  24  24  24  13  82   4
C |   0   0  56  24  24  24  24  24  24  24  24  24  24  24  23   4  84
G |  96  96   4  24  24  24  24  24  24  24  24  24  24  24  43   6   4
T |   0   0  17  24  24  24  24  24  24  24  24  24  24  24  17   4   4

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updated Mon Jan 5 22:08:43 2026