5txp_AB : 3D-footprint complex

structure name	STRUCTURE OF Q151M COMPLEX (A62V, V75I, F77L, F116Y, Q151M) MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DDATP
reference	Martinez et al.
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5txp_A interface=96,117,159,185,186,267,358,450, mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfvikkkdstkwrklidlrelnkrtqdfwevqlgIphpaglkkkksvtvldvgdaYysvpldedfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfkkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndicklvgklNwasqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyaRmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgaetfyvdgaanRetklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtnsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa > 5txp_B interface= pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaGlkkkksvtvldvgdayfsvpLdedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqSsmtkilepfkkqnpdiviyqymddlYVgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlsklLrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqKittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
interface signature	IYPYMNRR/GLSYVLK

Estimated binding specificities ?

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# IC=3.974 IC/col=0.234 n_of_columns=17

specificity:

A |   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24  76  20
C |   0   0  67  24  24  24  24  24  24  24  24  24  24  24  24   9  48
G |  96  96  11  24  24  24  24  24  24  24  24  24  24  24  24   0  19
T |   0   0   9  24  24  24  24  24  24  24  24  24  24  24  24  11   9

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updated Thu Jun 25 09:23:44 2026