5v0l_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE AHR-ARNT HETERODIMER IN COMPLEX WITH THE DRE (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR)
reference	Bradfield et al. 'Proc. 114 5431 2017
source	HOMO SAPIENS
experiment	X-ray (resolution=4.00, R-factor=0.287)
structural superfamily	HLH, helix-loop-helix DNA-binding domain;PYP-like sensor domain PAS domain;
sequence family	Helixloophelix DNAbinding domain; PAS fold;
multimeric complexes	5v0l_AB 7xhv_AB
redundant complexes	7xhv
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5v0l_A interface=14,18,21,22, qssadkerlarenHseiErrRRnkmtayitelsdmvptcsalarkpdkltilrmavshmkslkpsfltdqelkhlileaadgflfivscetgrvvyvsdsvtpqpqsewfgstlydqvhpddvdklreqlsgsrrsficrmrcephfvvvhctgydddpeagqgskfclvaigrlq
interface signature	HERR

Estimated binding specificities ?

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# IC=1.739 IC/col=0.348 n_of_columns=5

specificity:

A |  16  11  67  24   5
C |   5  28   5  24  84
G |  16  39  13  24   2
T |  59  18  11  24   5

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----HG----ETRTRG   L                        +-----5v0l_A    
                            +-----------------2 
  ----HG----ECRGRG   L      !                 +-----4zpk_A    
                         +--3 
  ----HGSTITETRCRG   L   !  !                       +4h10_A    
                       --4  +-----------------------1 
  KT--HGNT--ECRCRG   L   !                          +1nkp_A    
                         ! 
  --RGHGKT--EARCRC   L   +--------------------------1a0a_B

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updated Wed Dec 18 02:25:17 2024