5vl9_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF EILR IN COMPLEX WITH EILO DNA ELEMENT (Regulatory protein TetR)
reference	Tomaleri et al. 'Nat 9 3617 2018
source	Enterobacter lignolyticus
experiment	X-ray (resolution=2.16, R-factor=0.196)
structural superfamily	Homeodomain-like;Tetracyclin repressor-like, C-terminal domain;
sequence family	Bacterial regulatory proteins, tetR family;
multimeric complexes	5vl9_AD 5vl9_BC
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5vl9_A interface=2,30,31,40,43,45,46, gYlnreerretimqaamrvaldqgftgmtVRniataagvAagQvHHhftssgelksqafirviremmdlqrlsrtagwreqlfsalgsedgrlepyirlwrqaqlladsdpeiksaylltmnlwhdeavriiraghaageftlrdsaeniawrlislvcgldgiyvlgmpevddaaftrhlqhviqlelfs
interface signature	YVRAQHH

Estimated binding specificities ?

readout + contact

# IC=7.580 IC/col=0.947 n_of_columns=8

specificity:

A |   0   7   0   7   9  73   0  96
C |   0   9   0   7   7   7  96   0
G |  96   7   0  73  73   7   0   0
T |   0  73  96   9   7   9   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----ATYA--LTYTFT   L                      +-6en8_C    
                                      +-----2 
  ----SGKGPT--YG--   L                !     +-6o6p_B    
                                      ! 
  LG----KG--STYTHT   L   +------------6       +4l62_M    
                         !            !     +-1 
  LC--RTPTPTSTYT--   L   !            !   +-3 +6nsn_B    
                         !            !   ! ! 
  ------KG----YT--     --7            +---4 +--6wpa_A    
                         !                ! 
  --PTTCRG----YGHA   L   !                +---6c31_A    
                         ! 
  MTRGTGPT--ATYTWT   L   !               +----5yej_B    
                         +---------------5 
  MTRGAAVT--TTYT--   L                   +----5fmp_B

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updated Fri Sep 13 20:37:52 2024