interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTION FACTOR FOSB/JUND BZIP DOMAIN IN COMPLEX WITH COGNATE DNA, TYPE-I CRYSTAL
(PROTEIN FOSB)
referenceMachius et al. 'Nucleic 45 11425 2017
sourceHOMO SAPIENS
experimentX-ray (resolution=2.05, R-factor=0.219)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
redundant complexes5vpf
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNAAR

Estimated binding specificities ?

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# IC=3.088 IC/col=0.441 n_of_columns=7 specificity:   
A |  56   3   6  12  71  14  17
C |  13   4   7  61  10  66  39
G |  14  85   7  11   8   8  20
T |  13   4  76  12   7   8  20
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: FOSB
TGACTCAPubMed5vpe_C(1.04e-02)
term: JUND
TGCGTCAPubMed5vpe_C(1.04e-02)
|GTCAPubMed5vpe_C(1.01e-03)
TGAGTCAPubMed5vpe_C(1.04e-02)

Dendrogram of similar interfaces ?

matrix format



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updated Fri Sep 13 20:38:03 2024