interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTION FACTOR FOSB/JUND BZIP DOMAIN IN COMPLEX WITH COGNATE DNA, TYPE-I CRYSTAL
(PROTEIN FOSB)
referenceMachius et al. 'Nucleic 45 11425 2017
sourceHOMO SAPIENS
experimentX-ray (resolution=2.05, R-factor=0.219)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
redundant complexes5vpf
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNAAR

Estimated binding specificities ?

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# IC=3.212 IC/col=0.459 n_of_columns=7 specificity:   
A |  17   8   7  13  76   4  13
C |  22   8   8  11   7  86  13
G |  40  67   7  60   6   3  13
T |  17  13  74  12   7   3  57
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: FOSB
TGACTCAPubMed5vpe_C(1.04e-02)
term: JUND
TGCGTCAPubMed5vpe_C(1.04e-02)
|GTCAPubMed5vpe_C(1.01e-03)
TGAGTCAPubMed5vpe_C(1.04e-02)

Dendrogram of similar interfaces ?

matrix format



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updated Sun Aug  3 10:10:56 2025