5w66_ABMPQ : 3D-footprint complex

structure name	RNA POLYMERASE I INITIAL TRANSCRIBING COMPLEX STATE 3
experiment	NMR
reference complex	5w5y_P 5w5y_Q 5w66_M
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5w66_A interface=303,305,403,514,515,935,936,940,1134,1398,1414, mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrnlcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryacklrllqyglidesykldeitldisstllnelkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlpsklgeEvHensqnqllskvlttsllirdlnddlsklqkdkvsledrrvifsrlmnafvtiqndvnafidstkaqkvpipgvkqalekkeglfrkhmmgkrvnyaaRsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqnedgslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrQPtlhkasmmghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgildksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavkTSrsgYlqrcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehldvesalkyskktlkyrkkhsphykqsvkydpvlakynpakylgsvsenfqdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqmnvtlgiprlreivMtasaaiktpqmtlpiwndvsdeqadtfcksiskvllsevidkvivtettaarsyvihmrffdnneyseeydvskeelqnvisnqfihlleaaivkeikkqknmnkvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfrhldliadmmtrqgtylafnRqgmetstssfmkmsyEttcqfltkavldnereqldspsarivvgklnnvgtgsfdvlakvpna > 5w66_B interface=463,492, rtadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggllnlgvkdigekvifdgkplnsnsgylgnklsvsveqvsiakpmsndgvssaverkvypsesrqrltsyrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyelvqhkeesdeiggyfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvrpdqtsqtnvlhylndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkdsfltdrlelllrgfkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlvhlgkdgsqdkfrmllfmirklyslvagecspdnpdatqhqevllggflygmilkekideylqniiaqvrmdinrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlQqvsgytvvaekinfyrfishfrmvhrgsFfaqlktttvrkllpeswgflcpvhtpdgspcgllnhfahkcristqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheqgkiiadtlrywkvegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldkedivgpfeqvymniavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcqmgkqtmgtpgvalchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytgydmddamiinksadergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekldedglpyigtyveegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqtvsikyrirrtpqigdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmtigmfveslagkagalhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatgeelradiyvgvvyyqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdalighgtsfllqdrllnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakklltedgekifiddsqiwedgqgnkfvggnetttvaipfvlkyldselsamgirl > 5w66_M interface= seieiesvqdqpsvavgsffkgfrapsdttfdlykkkksekdefvlhgenerleyegytdsssqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkiksksdtrpsalrnalgeafgtkkakkaiadlernridsdkltdsaidivdsvrtaskdlptraqldeitsndrptplanidatdveqiypiesiipkkelqfirvssilkeadkekklelfpyqnnskyvakkldsltqpsqmtklqllyylslllgvyenrrvnnktkllerlnsppeilvdgilsrftvikpgqfgrskdrsyfidpqnedkilcyilaiimhldnfiveitplahelnlkpskvvslfrvlgaivkgatvaqaeafgipkstaasykiatmkvpfkl > 5w66_P interface=121,200,201,202, kligheakllflksfqfilkrqirwlitemrfpkefehvakiiwlkilktindqpqeelklqlhmtstisilylasthlslpvytcdyikwictakmpyfqaseilpkswriqlpnyyvsIlegsispfngqlynkialtcgmihfkeffnseiscqglllklvmqcalppefyfytkqviefeetdirnltlwertdeRHTgrvsnhaelrvlsyfmltinwmlsfdrdrqyplkwilsltesltqrtttsesigrnivkvvypdkptssdyfqwseeetleflkwmekqflptqtsmemtidqkiarrklykifpldredthqltfiedlqeryakqtpffpparkeaigrllthiasqllvdfaiskeqlkdcisriknaclhr > 5w66_Q interface=10,11,204, mfevpitltNRkfaqrrklkyqyinyisrrfdrisksdeerkfwkkyekpeksfeiwrtvssqnkqpinkqkmtyhnfkkiekiplrkmeipllhctkenklyfqsisrgleplktstsevrnyrtrhivtltdllhlnvsrhnwslaykifatliripgvqikslwgigveildnlsnsssgldflqwmcqiyssksrfvqnInyrsivppfqtgsrthtakfaitylwsslincqksmeptendllqelidkisewvltppfmedaevwfiyaschllkadtlsrqfvndnknndligldrdikinqvikhihyvrtflkicldkggfavpsrlienqlksfesrly
interface signature	EHRQPTSYMRE/QF//IRHT/NRI

Estimated binding specificities ?

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# IC=8.511 IC/col=0.243 n_of_columns=35

specificity:

A |   0  20  24  24  13  48  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  24  24  24  24  24  24  24  96  96
C |   0  15  24  24  16  20  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  24  24  24  24  24  24  24   0   0
G |   0  48  24  24  54  13  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0  24  24  24  24  24  24  24   0   0
T |  96  13  24  24  13  15  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96  96  96  24  24  24  24  24  24  24   0   0

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updated Tue Sep 10 09:31:29 2024