interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS FOR RECOGNITION OF ARTIFICIAL DNA BY AN EVOLVED KLENTAQ VARIANT
(DNA polymerase I, thermostable)
referenceGeorgiadis et al. 'Nucleic 46 7977 2018
sourceThermus aquaticus
experimentX-ray (resolution=2.66, R-factor=0.213)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYRNNH

Estimated binding specificities ?

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# IC=0.688 IC/col=0.172 n_of_columns=4 specificity:   
A |  20  17   9  20
C |  19  49   9  38
G |  38  15  67  19
T |  19  15  11  19
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updated Fri Jan 9 04:40:16 2026