5xn1_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE Q151M:DNA:ENTECAVIR-TRIPHOSPHATE TERNARY COMPLEX
reference	Yasutake et al. 'Sci 8 1624 2018
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.45, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xn1_A interface=22,23,59,61,72,74,76,92,113,181,182,446, spietvpvklkpgmdgpkvkqWPlteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdaYfsvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgspaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnqktelqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 5xn1_B interface=246,249, pietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnWasQiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WPFILDRIYYMR/WQ

Estimated binding specificities ?

contact

# IC=9.270 IC/col=0.281 n_of_columns=33

specificity:

A |   0   0   8   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   8   0  19
C |   0  96   8  96  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   8   0  61
G |   0   0  63   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  72  96   8
T |  96   0  17   0  24  24  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24   8   0   8

scan!

home
updated Mon Jan 5 23:48:12 2026