5xn2_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE Q151M:DNA:DGTP TERNARY COMPLEX
reference	Yasutake et al. 'Sci 8 1624 2018
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.38, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5xn2_C interface=22,59,61,72,74,76,92,113,155,181,182,446,473,499, spietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdaYfsvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 5xn2_D interface= pietvpvklkpgmdgpkvkqwPlteekikalveictemekegkiskigpenpyntpvfAiKkkdstkwrklVdFrElnkrtqdfwevqlgiPhpaglkqkksvtvldvgdayFsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspAifqssmtkilepfrkqnpdiviyqyMDdlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFILDRIYPYMRQY/PAKVFEPFAMD

Estimated binding specificities ?

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# IC=9.761 IC/col=0.296 n_of_columns=33

specificity:

A |   0   0   0   5  24  24  24  24  24  24  24  24  24  24  24   4  24   6   4  24  24  24  24  24  24  24  24  24  24  24   4   0   8
C |   0  96   4  87  24  24  24  24  24  24  24  24  24  24  24   0  24   4  13  24  24  24  24  24  24  24  24  24  24  24   6   0  71
G |   0   0  92   4  24  24  24  24  24  24  24  24  24  24  24   5  24   4  69  24  24  24  24  24  24  24  24  24  24  24  82  96  13
T |  96   0   0   0  24  24  24  24  24  24  24  24  24  24  24  87  24  82  10  24  24  24  24  24  24  24  24  24  24  24   4   0   4

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updated Mon Jan 5 23:49:50 2026