interface graph thumbnail
legend  pdf

structure nameLARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH THE UNNATURAL BASE M-FC PAIR WITH DATP IN THE ACTIVE SITE
(DNA polymerase I, thermostable)
referenceMondal et al. 'Angew. 58 130 2019
sourceThermus aquaticus
experimentX-ray (resolution=2.28, R-factor=0.197)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNQH

Estimated binding specificities ?

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# IC=2.522 IC/col=0.630 n_of_columns=4 specificity:   
A |  24   0   6   0
C |  18  96  12  30
G |  42   0  72   6
T |  12   0   6  60
scan!

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updated Mon Dec 18 14:08:12 2023