interface graph thumbnail
legend  pdf

structure nameLARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH THE NATURAL BASE PAIR 5FC:DGTP
(DNA polymerase I, thermostable)
referenceMondal et al. 'Angew. 58 130 2019
sourceThermus aquaticus
experimentX-ray (resolution=2.00, R-factor=0.198)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNH

Estimated binding specificities ?

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# IC=3.120 IC/col=0.780 n_of_columns=4 specificity:   
A |   0   0   2  11
C |   9  96   9  38
G |  87   0  76  19
T |   0   0   9  28
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updated Sun Jun 28 14:32:32 2026