interface graph thumbnail
legend  pdf

structure nameLARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH THE NATURAL BASE PAIR 5FC:DGTP
(DNA polymerase I, thermostable)
referenceMondal et al. 'Angew. 58 130 2019
sourceThermus aquaticus
experimentX-ray (resolution=2.00, R-factor=0.198)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNH

Estimated binding specificities ?

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# IC=2.791 IC/col=0.698 n_of_columns=4 specificity:   
A |  11   0  11   9
C |   9  96   0  59
G |  67   0  76   9
T |   9   0   9  19
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updated Sat Aug 2 10:03:51 2025