interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS HOST-GUEST COMPLEX WITH THE UNNATURAL BASE 5FC PAIR WITH DA
(DNA polymerase I, thermostable)
referenceMondal et al. 'Angew. 58 130 2019
sourceThermus aquaticus
experimentX-ray (resolution=1.91, R-factor=0.186)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNQH

Estimated binding specificities ?

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# IC=2.674 IC/col=0.669 n_of_columns=4 specificity:   
A |   9   0  11   9
C |   9  96   9  67
G |  69   0  67  11
T |   9   0   9   9
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updated Sat Aug 2 10:10:17 2025