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structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A11G DNA MUTANT
(Double homeobox protein 4-like protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=0.194)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes5z2t_CD 6dfy_CD
reference complex6a8r_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

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# IC=10.435 IC/col=0.870 n_of_columns=12 specificity:   
A |   8   0  96  96   8  11   0  24  24   1   0  96
C |  69   0   0   0  11  69   0  24  24   8  96   0
G |  11   0   0   0   8   8   0  24  24   0   0   0
T |   8  96   0   0  69   8  96  24  24  87   0   0
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updated Sun Jun 28 14:44:54 2026