5zfw_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A11G DNA MUTANT (Double homeobox protein 4-like protein 4)
reference	Gan et al. 'Biochem. 505 1161 2018
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=0.194)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	5z2t_CD 6dfy_CD
reference complex	6a8r_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5zfw_A interface=2,5,47,50,51,54,68,71,113,116,117,121, gRrrRlvwtpsqsealracfernpypgiatrerlaqaigipeprvqIwfQNerSrqlrqhrrespegRrkRtavtgsqtalllrafekdrfpgiaareelaretglpesriqIwfQNrraRh
interface signature	RRIQNSRRIQNR

Estimated binding specificities ?

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# IC=10.523 IC/col=0.877 n_of_columns=12

specificity:

A |   8   0  96  96  11   8   0  24  24   0   0  96
C |  69   0   0   0   8  72   0  24  24   9  96   0
G |  11   0   0   0   8   8   0  24  24   0   0   0
T |   8  96   0   0  69   8  96  24  24  87   0   0

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updated Fri Jan 9 05:16:20 2026