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structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A11G DNA MUTANT
(Double homeobox protein 4-like protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.10, R-factor=0.194)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

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# IC=10.526 IC/col=0.877 n_of_columns=12 specificity:   
A |   0   0  88  24  24  96   8  72   0   0  96   8
C |   0   0   0  24  24   0   8   8   0   0   0   8
G |   0  96   8  24  24   0  64   8   0   0   0  72
T |  96   0   0  24  24   0  16   8  96  96   0   8
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updated Sat Aug 2 10:13:30 2025