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structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12C DNA MUTANT
(Double homeobox protein 4-like protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.186)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNRSRRIQNR

Estimated binding specificities ?

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# IC=10.292 IC/col=0.858 n_of_columns=12 specificity:   
A |   0   0  96  24  24  56   8  88   0   0  96   8
C |   0   0   0  24  24  24   8   0   0   0   0  16
G |   0  96   0  24  24   8  72   8   0   0   0  64
T |  96   0   0  24  24   8   8   0  96  96   0   8
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updated Thu Sep 12 22:38:21 2024