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structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12C DNA MUTANT
(Double homeobox protein 4-like protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.186)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNRSRRIQNR

Estimated binding specificities ?

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# IC=10.654 IC/col=0.888 n_of_columns=12 specificity:   
A |  10   0  96  96   0   9   9  24   9   0   0  96
C |  73   0   0   0  14  64  19  24  10   0  96   0
G |   9   0   0   0   0  10   9  24   9   0   0   0
T |   4  96   0   0  82  13  59  24  68  96   0   0
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updated Sat Aug 2 10:13:37 2025