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structure nameCRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12C DNA MUTANT
(Double homeobox protein 4-like protein 4)
referenceGan et al. 'Biochem. 505 1161 2018
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.186)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes5z2t_CD 6dfy_CD
reference complex6a8r_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNRSRRIQNR

Estimated binding specificities ?

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# IC=10.707 IC/col=0.892 n_of_columns=12 specificity:   
A |   9   0  96  96   0  18   7  24  22   0   0  96
C |  81   0   0   0   7  49  14  24  11   0  96   0
G |   3   0   0   0   1   7   9  24   8   0   0   0
T |   3  96   0   0  88  22  66  24  55  96   0   0
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updated Fri Jan 9 05:16:28 2026