interface graph thumbnail
legend  pdf

structure nameZINC FINGER DOMAIN OF WT1(+KTS FORM) WITH M342R MUTATION AND 17+1MER OLIGONUCLEOTIDE WITH TRIPLET GGT
(Wilms tumor protein)
referenceHorton et al. 'Nucleic 46 3864 2018
sourceHomo sapiens
experimentX-ray (resolution=1.83, R-factor=0.223)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSHRRDQRRSDH

Estimated binding specificities ?

readout + contactlogo
# IC=8.121 IC/col=0.902 n_of_columns=9 specificity:   
A |  66  24   0   0   0  10   0   0   0
C |  10  24  96  96  96  12  96  96  74
G |  10  24   0   0   0  10   0   0  12
T |  10  24   0   0   0  64   0   0  10
scan!

home
updated Fri Sep 13 21:20:03 2024