interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYO-EM STRUCTURE OF CENP-A NUCLEOSOME IN COMPLEX WITH KINETOCHORE PROTEIN CENP-N
(HISTONE H3-LIKE CENTROMERIC PROTEIN A)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes3an2_ABCDEFGH 3wtp_ABCDEFGH 6buz_ABCDEFGHN 6l49_ABCDEFGHKLMNOPQRSTUVWXYZ 7d20_ABCDEFGH
redundant complexes3an2 3wtp 6l49 7d20
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --RC--         +-----------------------------7ux9_E    
               +-8 
  --RT--       ! +-----------------------------6px1_A    
               ! 
  --RA--       !                          +--7xsx_a    
               !            +-------------3 
  --RA--     --9            !             +--7e9c_F    
               !        +---6 
  --RARA       !        !   !                +6a5l_g    
               !        !   ! +--------------1 
  --RG--       !        !   +-4              +8upf_G    
               !        !     ! 
  --RG--       +--------7     +--------------8txv_G    
                        ! 
  --RT--                !                   +8u14_G    
                        !    +--------------2 
  --RC--                +----5              +7yqk_C    
                             ! 
  HGRG--                     +---------------8rbx_V    
             

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updated Sat Jan 10 09:46:59 2026