6d8a_A : 3D-footprint complex

structure name	RSAGO TERNARY COMPLEX WITH GUIDE RNA AND TARGET DNA CONTAINING A-A BULGE WITHIN THE SEED SEGMENT OF THE TARGET STRAND (Uncharacterized protein)
reference	Olovnikov et al. 'Cell 24 453 2018
source	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) / Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 478;
reference complex	6d92_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6d8a_A interface=26,44,226,310,322,472,475,476,479,587,621,637,642,651,668,670,671,673,675,708,715,716, rqlvsngfevnlpdqvevivrdlpdPskvkeertrlmgywfvhWfdgklfhlrikaggpnvdgehrairtaehpwllrarlddaleealpkyaavkkrpftflaqkdelidaaataaglshrllnsfkviprfalspkiyepvdgttrvgvfvtigmrydieaslrdlleagidlrgmyvvrrkrqpgergllgrvraisddmvqlfeetdlasvnvndaklegsKenftrclsallghnykkllnalddqeagyrtgprfddavrrmgeflakkpirladninaqvgdrivfsnegqarnvrlapkveYvfdrtgaksaeYawrglsqfgpfdrpsfanrsprilvvypsstqgkvenflsafrdgmgsnysgfskgfvdlmgltkvefvmcpvevssadrngahtkynsaiedklagagevhagivvlfedharlpddrnpyihtksllltlgvptqqvrmptvllepkSlqYTlqNfsiatyaklngtpwtvnhdkaindelvvgmglaelsgsrtekrqrfvgittvfagdgsyllgnvskeceyegysdairesmtgilrelkkrnnwrpgdtvrvvfhahRplkrvdvasivfectreigsdqniqmafvtvshDhpfvlidrsergleaYkgstArkgvfappRgaisrvgrltrllavnSpQLiKrAntplptpllvslhpdstfkdvdylaeqalkftSlswrstLPaatpvtifyseriaellgrlksipnwssanlniklkwsrwfl
interface signature	PWKYYSYTNRDYARSQLKASLP

Estimated binding specificities ?

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# IC=10.098 IC/col=0.531 n_of_columns=19

specificity:

A |   5   0  24  24  24  11   5  24  24  24   5   5  24   0  96  24  24  96  96
C |  79   0  24  24  24  75  81  24  24  24   5  75  24   0   0  24  24   0   0
G |   7  96  24  24  24   5   5  24  24  24  79   5  24  96   0  24  24   0   0
T |   5   0  24  24  24   5   5  24  24  24   7  11  24   0   0  24  24   0   0

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updated Thu Sep 12 23:00:19 2024