6d8p_B : 3D-footprint complex

structure name	TERNARY RSAGO COMPLEX CONTAINING GUIDE RNA PAIRED WITH TARGET DNA (Uncharacterized protein)
reference	Olovnikov et al. 'Cell 24 453 2018
source	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) / Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
experiment	X-ray (resolution=2.10, R-factor=0.184)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 478;
reference complex	6d92_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6d8p_B interface=26,44,220,304,316,319,466,469,470,473,581,615,645,662,664,665,667,702,709,710, rqlvsngfevnlpdqvevivrdlpdPskvkeertrlmgywfvhWfdgklfhlrikaggpnvdgehrairtaehpwllrarlddaleealpkyaavkkrpftflaqkdelidaaataaglshrllnsfkviprfalspkiyepvdgttrvgvfvtigmrydieaslrdlleagidlrgmyvvrrkrqrgllgrvsddmvqlfeetdlasvnvndaklegsKenftrclsallghnykkllnalddqeagyrtgprfddavrrmgeflakkpirladninaqvgdrivfsnegqarnvrlapkveYvfdrtgaksaeYawRglsqfgpfdrpsfanrsprilvvypsstqgkvenflsafrdgmgsnysgfskgfvdlmgltkvefvmcpvevssadrngahtkynsaiedklagagevhagivvlfedharlpddrnpyihtksllltlgvptqqvrmptvllepkSlqYTlqNfsiatyaklngtpwtvnhdkaindelvvgmglaelsgsrtekrqrfvgittvfagdgsyllgnvskeceyegysdairesmtgilrelkkrnnwrpgdtvrvvfhahRplkrvdvasivfectreigsdqniqmafvtvshDhpfvlidrsergleaykgstarkgvfappRgaisrvgrltrllavnSpQLiKrantplptpllvslhpdstfkdvdylaeqalkftSlswrstLPaatpvtifyseriaellgrlksipnwssanlniklkwsrwfl
interface signature	PWKYYRSYTNRDRSQLKSLP

Estimated binding specificities ?

contact

# IC=9.834 IC/col=0.546 n_of_columns=18

specificity:

A |   5   5  24  24  81   5   5  24  24  24   0  24  24   6  24  96  96   0
C |  81   6  24  24   5  80  81  24  24  24   0  24  24   5  24   0   0  96
G |   5  80  24  24   5   5   5  24  24  24  96  24  24  80  24   0   0   0
T |   5   5  24  24   5   6   5  24  24  24   0  24  24   5  24   0   0   0

scan!

home
updated Thu Sep 12 23:00:42 2024