6d95_A : 3D-footprint complex

structure name	TERNARY RSAGO COMPLEX WITH GUIDE RNA PAIRED AND TARGET DNA CONTAINING A8-A8' NON-CANONICAL PAIR (Uncharacterized protein)
reference	Olovnikov et al. 'Cell 24 453 2018
source	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) / Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
experiment	X-ray (resolution=1.85, R-factor=0.212)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 478;
reference complex	6d92_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6d95_A interface=26,44,226,310,322,472,475,476,479,513,587,621,651,668,670,671,673,708,715,716, rqlvsngfevnlpdqvevivrdlpdPskvkeertrlmgywfvhWfdgklfhlrikaggpnvdgehrairtaehpwllrarlddaleealpkyaavkkrpftflaqkdelidaaataaglshrllnsfkviprfalspkiyepvdgttrvgvfvtigmrydieaslrdlleagidlrgmyvvrrkrqpgergllgrvraisddmvqlfeetdlasvnvndaklegsKenftrclsallghnykkllnalddqeagyrtgprfddavrrmgeflakkpirladninaqvgdrivfsnegqarnvrlapkveYvfdrtgaksaeYawrglsqfgpfdrpsfanrsprilvvypsstqgkvenflsafrdgmgsnysgfskgfvdlmgltkvefvmcpvevssadrngahtkynsaiedklagagevhagivvlfedharlpddrnpyihtksllltlgvptqqvrmptvllepkSlqYTlqNfsiatyaklngtpwtvnhdkaindelvvgmglaElsgsrtekrqrfvgittvfagdgsyllgnvskeceyegysdairesmtgilrelkkrnnwrpgdtvrvvfhahRplkrvdvasivfectreigsdqniqmafvtvshDhpfvlidrsergleaykgstarkgvfappRgaisrvgrltrllavnSpQLiKrantplptpllvslhpdstfkdvdylaeqalkftSlswrstLPaatpvtifyseriaellgrlksipnwssanlniklkwsrwfl
interface signature	PWKYYSYTNERDRSQLKSLP

Estimated binding specificities ?

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# IC=9.823 IC/col=0.546 n_of_columns=18

specificity:

A |   3   3  24  24  24  14   3  24  24  24   3   3  24   6  24  96  96   0
C |  84   6  24  24  24  72  84  24  24  24   3  84  24   3  24   0   0  96
G |   6  84  24  24  24   3   3  24  24  24  87   6  24  84  24   0   0   0
T |   3   3  24  24  24   7   6  24  24  24   3   3  24   3  24   0   0   0

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updated Sat Aug 2 10:40:14 2025