6d95_A : 3D-footprint complex

structure name	TERNARY RSAGO COMPLEX WITH GUIDE RNA PAIRED AND TARGET DNA CONTAINING A8-A8' NON-CANONICAL PAIR (Uncharacterized protein)
reference	Olovnikov et al. 'Cell 24 453 2018
source	Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) / Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
experiment	X-ray (resolution=1.85, R-factor=0.212)
structural superfamily	Ribonuclease H-like;
sequence family	Piwi domain 478;
reference complex	6d92_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6d95_A interface=26,44,226,310,322,472,475,476,479,513,587,621,651,668,670,671,673,708,715,716, rqlvsngfevnlpdqvevivrdlpdPskvkeertrlmgywfvhWfdgklfhlrikaggpnvdgehrairtaehpwllrarlddaleealpkyaavkkrpftflaqkdelidaaataaglshrllnsfkviprfalspkiyepvdgttrvgvfvtigmrydieaslrdlleagidlrgmyvvrrkrqpgergllgrvraisddmvqlfeetdlasvnvndaklegsKenftrclsallghnykkllnalddqeagyrtgprfddavrrmgeflakkpirladninaqvgdrivfsnegqarnvrlapkveYvfdrtgaksaeYawrglsqfgpfdrpsfanrsprilvvypsstqgkvenflsafrdgmgsnysgfskgfvdlmgltkvefvmcpvevssadrngahtkynsaiedklagagevhagivvlfedharlpddrnpyihtksllltlgvptqqvrmptvllepkSlqYTlqNfsiatyaklngtpwtvnhdkaindelvvgmglaElsgsrtekrqrfvgittvfagdgsyllgnvskeceyegysdairesmtgilrelkkrnnwrpgdtvrvvfhahRplkrvdvasivfectreigsdqniqmafvtvshDhpfvlidrsergleaykgstarkgvfappRgaisrvgrltrllavnSpQLiKrantplptpllvslhpdstfkdvdylaeqalkftSlswrstLPaatpvtifyseriaellgrlksipnwssanlniklkwsrwfl
interface signature	PWKYYSYTNERDRSQLKSLP

Estimated binding specificities ?

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# IC=9.192 IC/col=0.511 n_of_columns=18

specificity:

A |   2  11  24  24  24  16   9  24  24  24   2   2  24   2  24  96  96   0
C |  88   2  24  24  24  45  67  24  24  24   2  88  24   2  24   0   0  96
G |   4  74  24  24  24  21  11  24  24  24  90   4  24  88  24   0   0   0
T |   2   9  24  24  24  14   9  24  24  24   2   2  24   4  24   0   0   0

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updated Tue Dec 17 03:39:03 2024