| structure name | KAISO (ZBTB33) K539A ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH THE SPECIFIC KAISO BINDING SEQUENCE (KBS) (Transcriptional regulator Kaiso) |
| reference | Stanfield et al. Biochemistry ? ? 2020 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.66, R-factor=0.181) |
| structural superfamily | beta-beta-alpha zinc fingers; |
| sequence family | Zinc finger, C2H2 type; |
| redundant complexes | 6v8u 5vmu 5vmv 5vmw 5vmx 5vmy 5vmz 6df5 6df8 6df9 6dfa 6dfc 2lt7 4f6m 4f6n |
| reference complex | 2lt7_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | TSRLEYNYQRY |
Estimated binding specificities ?
| readout + contact |  |
A | 10 0 0 0 0 0 0 66 C | 10 96 85 0 0 96 85 10 G | 12 0 1 0 96 0 1 10 T | 64 0 10 96 0 0 10 10scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: KAISO | ||
| CTGCNA | PubMed | 6dfb_A(1.88e-05), 6v8u_A(6.52e-03), 4f6m_A(2.01e-05), ... (total=9) |
| TCCTGCNA | PubMed | 6dfb_A(2.83e-10), 5vmw_A(1.20e-05), 5vmx_A(9.93e-06), ... (total=12) |
| TNGCAGGA | PubMed | 6dfb_A(2.83e-10), 5vmw_A(1.20e-05), 5vmx_A(9.93e-06), ... (total=12) |
| TCTCGCGAGA | PubMed | 5vmw_A(1.18e-07), 5vmx_A(1.14e-07), 5vmy_A(1.14e-07) |
| NCTGCCA | PubMed | 6dfb_A(1.57e-07), 6v8u_A(1.73e-04), 4f6m_A(1.93e-07), ... (total=9) |
Dendrogram of similar interfaces ?
matrix formatECSCKGRG--DCTCYCKGRG--QA--TC---- L +----------5und_A +------2 DCYCKGRG--QA----TC----RCSCDC--VT L ! ! +--------5k5i_A --3 +-1 ----------DC--SCQGKTTTATSCSC---- L ! +--------6ml4_A ! --------RGST--YGYC----QCTGSTRAYT L +-----------------3uk3_C |
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updated Tue Dec 17 03:45:24 2024