6fqs_ABCD : 3D-footprint complex

structure name	3.11A COMPLEX OF S.AUREUS GYRASE WITH IMIDAZOPYRAZINONE T3 AND DNA
reference	Maxwell et al. 'Nucleic 46 4114 2018
source	STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experiment	X-ray (resolution=3.11, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqs_A interface=24,75,76,79,83,166, nernitsemresfldyamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyEamvRmaqdfsyryplvdgqgnfgsmdgdgaaamrytearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqs_B interface=44, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya > 6fqs_C interface=24,75,76,113,165,222,320, nernitsemresfldyamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRtearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirRayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtSfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqs_D interface=44, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavy
interface signature	RSSERI/K/RSSRIRS/K

Estimated binding specificities ?

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# IC=10.290 IC/col=0.605 n_of_columns=17

specificity:

A |   0  24  24  96   0  24  87  13  24  24  24  16  75   3  62   0   0
C |   0  24  24   0   0  24   3  11  24  24  24  62   6   3  13  96   0
G |  96  24  24   0  96  24   3  13  24  24  24   9   9   0  12   0   0
T |   0  24  24   0   0  24   3  59  24  24  24   9   6  90   9   0  96

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updated Wed Jul 30 17:54:24 2025