6fqs_ABCD : 3D-footprint complex

structure name	3.11A COMPLEX OF S.AUREUS GYRASE WITH IMIDAZOPYRAZINONE T3 AND DNA
reference	Maxwell et al. 'Nucleic 46 4114 2018
source	STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experiment	X-ray (resolution=3.11, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqs_A interface=24,75,76,79,83,166, nernitsemresfldyamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyEamvRmaqdfsyryplvdgqgnfgsmdgdgaaamrytearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqs_B interface=44, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya > 6fqs_C interface=24,75,76,113,165,222,320, nernitsemresfldyamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRtearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirRayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtSfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqs_D interface=44, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavy
interface signature	RSSERI/K/RSSRIRS/K

Estimated binding specificities ?

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# IC=9.562 IC/col=0.562 n_of_columns=17

specificity:

A |  96   0  10  90  10  24  24  24  24  64   5  24   0   0  24  24   0
C |   0   0  18   1  12  24  24  24  24  10   5  24  96   0  24  24   0
G |   0  96  10   0  10  24  24  24  24  12   5  24   0   0  24  24   0
T |   0   0  58   5  64  24  24  24  24  10  81  24   0  96  24  24  96

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updated Tue Sep 10 13:25:59 2024