6gys_ACEHJL : 3D-footprint complex

structure name	CRYO-EM STRUCTURE OF THE CBF3-CEN3 COMPLEX OF THE BUDDING YEAST KINETOCHORE
reference	McLaughlin et al. 'Nat. 25 1103 2018
source	SACCHAROMYCES CEREVISIAE
experiment	X-ray (resolution=4.40, R-factor=?)
structural superfamily	Zn2/Cys6 DNA-binding domain;
reference complex	6gys_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6gys_A interface= sfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpskrskkllrymypvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalewtyldnelrlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlvdkclsileqkdlfatigevqfgqdnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnpgktisyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfksltmkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkseinqitylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlvi > 6gys_C interface=16,314,315,318,351, tqlkskhpcsvctrrKvkcdrmipcgncrkrgqdsecmkstitassskeylpdlllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfamenlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympveklaeifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylilatttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcdylqsgprkpialhtevssllQHaaYlqdnstevlywkiisldrdldqylnksskpplKtldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielkndemfslikglgslvplnsdfrtiveefqseynisdils > 6gys_E interface=302,304, edrfqelvdslkprtahqyktyytkyiqwcqlnqiiptnsvpykdlpisaelihwflldtlitddkpgekreetedldeeeensfkiatlkkiigslnflsklckvhenpnanidtkylesvtklhthwidsqkaittnetnntntqvlcppllkvslnlwnpetnhlsekffktcseklrflvdfqlrsylnlsfeerskirfgslklgkrdrdaiiyhkvthsaekkdtpghhqllallpqdcpficpqttlaaylylrfygipsvskgdgfpnlnadengsllqdipilrgkslttypReEtfsnyyttvfrychlpykrreyfnkcnlvyptwdedtfrtffneenhgnwleqpeafafpdkipfdfkkimnfkspytsystnakkdpfpppkdllvqifpeideykrhdyeglsqnsrdfldlmevlrerflsnlpwiykffpnhdifqdpifgnsdfqsyfndktihskgspilsfdilpgfnkiyknktnfysllierp > 6gys_H interface= sfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpskrskkllrymypvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalewtyldnelrlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlvdkclsileqkdlfatigevqfgqdnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnpgktisyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfksLtMkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkseinqitylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlvi > 6gys_J interface=12,21,25, hpcsvctrrkvKcdrmipcgNcrkRgqdsecmkstitassskeylpdlllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfamenlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympveklaeifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylilatttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcdylqsgprkpialhtenstevlywkiisldrdldqylnksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielkndemfslikglgslvplnsdfrtiveefqseynisdils > 6gys_L interface=302, edrfqelvdslkprtahqyktyytkyiqwcqlnqiiptnsvpykdlpisaelihwflldtlitddkpgekreetedldeeeensfkiatlkkiigslnflsklckvhenpnanidtkylesvtklhthwidsqkaittnetnntntqvlcppllkvslnlwnpetnhlsekffktcseklrflvdfqlrsylnlsfeerskirfgslklgkrdrdaiiyhkvthsaekkdtpghhqllallpqdcpficpqttlaaylylrfygipsvskgdgfpnlnadengsllqdipilrgkslttypReetfsnyyttvfrychlpykrreyfnkcnlvyptwdedtfrtffneenhgnwleqpeafafpdkipfdfkkimnfkspytsystnakkdpfpppkdllvqifpeideykrhdyeglsqnsrdfldlmevlrerflsnlpwiykffpnhdifqdpifgnsdfqsyfndktihskgspilsfdilpgfnkiyknktnfysllierp
interface signature	/KQHYK/RE/LM/KNR/R

Estimated binding specificities ?

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# IC=4.475 IC/col=0.224 n_of_columns=20

specificity:

A |  96  24  24   0  13  24  24  24  24  24  24  24  24  24  13  24  24  24  24   0
C |   0  24  24   0  54  24  24  24  24  24  24  24  24  24  13  24  24  24  24   0
G |   0  24  24   0  13  24  24  24  24  24  24  24  24  24  13  24  24  24  24  96
T |   0  24  24  96  16  24  24  24  24  24  24  24  24  24  57  24  24  24  24   0

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updated Tue Sep 10 13:52:14 2024