6h1v_A : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF POL2CORE IN COMPLEX WITH DNA AND AN INCOMING NUCLEOTIDE, CARRYING AN FE-S CLUSTER (DNA polymerase epsilon catalytic subunit A)
reference	Johansson et al. 'Nucleic 47 5712 2019
source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) / Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
experiment	X-ray (resolution=2.70, R-factor=0.240)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
sequence family	DNA polymerase family B, exonuclease do; DNA polymerase family B 900;
reference complex	4m8o_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6h1v_A interface=894,915, alsaqqllnaskiddidsmmgferyvppqyngrfdakdidqipgrvgwltnmhatlvsqenqgisgvdfyfldeeggsfkstvvydpyffiacndesrvndveelvkkylesclkslqiirkedltmdnhllglqktliklsfvnsnqlfearkllrpilqdnannnvqrniynvdakhliedireydvpyhvrvsidkdirvgkwykvtqqgfiedtrkiafadpvvmafaiattkpplkfpdsavdqimmisymidgegflitnreiisediedfeytpkpeypgfftifnendevallqrffehirdvrptvistfngdffdwpfihnrskihgldmfdeigfapdaegeykssycshmdcfrwvkrdsylpqgsqglkavtqsklgynpieldpelmtpyafekpqhlseysvsdavatyylymkyvhpfifslctiiplnpdetlrkgtgtlcemllmvqayqhnillpnkhtdpierfydghllesetyvgghvesleagvfrsdlknefkidpsaidellqelpealkfsvevenkssvdkvtnfeeiknqitqkllelkennirnelpliyhvdvasmypnimttnrlqpdsikaerdcktcarklkwawrgeffpskmdeynmikralqnetfpnkkvltfdelsyadqvihikkrlteysrkvyhrvkvseivereaivcqrenpfyvdtvksfrdrryefkglaktwkgnlskidpsdkhardeakkmivlydslqlahkvilnsfygyvmrkgsrwysmemagitcltgatiiqmaralvervgrpleldtdgiwcilpksfpetyfftlengkklylsypcsmlnyrvhqkftnhqyqelkdplnyiyethsentiffevdgpykamilpsskeegkgikKryavfnedgslaelkgfelkRrgelqliknfqsdifkvflegdtlegcysavasvcnrwldvldshglmlededlvslicenrsmsktlkeyegqkstsittarrlgdflgedmvkdkglqckyiisskpfnapvteraipvaifsadipikrsflrrwtldpsledldirtiidwgyyrerlgsaiqkiitipaalqgvsnpvprvehpdwlkrkiatk
interface signature	KR

Estimated binding specificities ?

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# IC=0.403 IC/col=0.101 n_of_columns=4

specificity:

A |  14  20  19  20
C |  56  19  19  19
G |  13  38  19  19
T |  13  19  39  38

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updated Fri Jan 9 06:30:16 2026