6ik9_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:DGTP TERNARY COMPLEX
reference	Hattori et al. 'Biochem. 509 943 2019
source	HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.44, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6ik9_A interface=24,61,74,78,94,157,183,184,265,448, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvdfRelnkrtqdfwevqlgIphpaglkqkksvtvldvsaafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPallqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnqktelqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6ik9_B interface=245,248,325, ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnWasQiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepFknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLRIPYMNR/WQF

Estimated binding specificities ?

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# IC=9.337 IC/col=0.283 n_of_columns=33

specificity:

A |   0   0   9   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   9   0   9
C |   0  96   9  96  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24   9   0  67
G |   0   0  67   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  69  96  11
T |  96   0  11   0  24  24  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24   9   0   9

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updated Tue Jan 6 04:52:48 2026