6ika_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:ENTECAVIR-TRIPHOSPHATE TERNARY COMPLEX
reference	Hattori et al. 'Biochem. 509 943 2019
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 / HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6ika_C interface=24,61,74,76,78,94,157,183,184,265,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvsaafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPallqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6ika_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkdstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIPYMNQY/EKRLKAQLYT

Estimated binding specificities ?

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# IC=9.632 IC/col=0.292 n_of_columns=33

specificity:

A |   0   0   5   0  24  14  24  24  24  24  24  24  24  24  24   3  24  24   3  24  24  24  24  24  24  24  24  24  24  24   3   0   5
C |   0  96   3  96  24  56  24  24  24  24  24  24  24  24  24   3  24  24  10  24  24  24  24  24  24  24  24  24  24  24   5   0  74
G |   0   0  85   0  24  12  24  24  24  24  24  24  24  24  24   3  24  24  78  24  24  24  24  24  24  24  24  24  24  24  85  96  14
T |  96   0   3   0  24  14  24  24  24  24  24  24  24  24  24  87  24  24   5  24  24  24  24  24  24  24  24  24  24  24   3   0   3

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updated Thu Jun 25 15:54:52 2026