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structure nameCRYOEM STRUCTURE OF ESCHERICHIA COLI SIGMAE TRANSCRIPTION INITIATION COMPLEX CONTAINING 5NT OF RNA
(ECF RNA POLYMERASE SIGMA-E FACTOR)
sourceESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experimentNMR
structural superfamilySigma2 domain of RNA polymerase sigma factors;Sigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence familySigma70 region 2; Sigma70, region 4;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPSKASFRDTWYRINKNVREFYTRSFR

Estimated binding specificities ?

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# IC=15.201 IC/col=0.490 n_of_columns=31 specificity:   
A |   0   4   7  96  96   0   4  24  24  24  24  24  24  24  24  24  24  24  24  24  84  24   4   0   0   0  24  24  96  24   7
C |  96   4   4   0   0  92   7  24  24  24  24  24  24  24  24  24  24  24  24  24   4  24   7   0   0  96  24  24   0  24  81
G |   0  81  81   0   0   0   4  24  24  24  24  24  24  24  24  24  24  24  24  24   4  24   4  96   0   0  24  24   0  24   4
T |   0   7   4   0   0   4  81  24  24  24  24  24  24  24  24  24  24  24  24  24   4  24  81   0  96   0  24  24   0  24   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----SC--PTSC--KTATSCFCRC--DC------TAWTYARTIT--NT--KCNC--VTRAEG--FG----YA------TGRTSGFTRC--   L                   +-------6jbq_F    
                                                                                                              +----1 
  DGQG--LG--PG--KT----FTRT----TTNTKGAGWTYGRTITTGNTYAICNCYA--RG------PCFCYG------TGMGSG--RGQC   L        +-----2    +-------5zx2_F    
                                                                                                        !     ! 
  ------------FG------FAEARA--FAKTSTTAYATCWT----------------------------LTTTRGECRCRTQC------   L   +----3     +------------4xln_F    
                                                                                                   !    ! 
  DG----LG--PG--KT----FTRT----TTNT--AGWTYGRTITTGNT--------------PT--------------------------     --4    +------------------6jcy_F    
                                                                                                   ! 
  ----------------------------------------------------------------------LG------TAKGTAHTRG--   L   +-----------------------6jhe_A    
                                                                                                 

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updated Tue Dec 17 04:33:24 2024