6kda_AD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HUMAN DNMT3B-DNMT3L IN COMPLEX WITH DNA CONTAINING CPGPG SITE
reference	Chen et al. 'Nucleic 48 3949 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.91, R-factor=?)
structural superfamily	S-adenosyl-L-methionine-dependent methyltransferases;
reference complex	6kdb_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kda_A interface=87,88,90,208,209,210, mrrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvqtittKSNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface > 6kda_D interface=87,88,90,203,208,209,210, mrrrpirvlslfdgiatgylvlkelgikvgkyvasevceesiavgtvkhegnikyvndvrnitkknieewgpfdlviggspcndlsNVnParkglyegtgrlffefyhllnysrpkegddrpffwmfenvvamkvgdkrdisrflecnpvmidaikvsaahraryfwgnlpgmnrpviaskndklelqdcleynriaklkkvQtittKSNsikqgknqlfpvvmngkedvlwctelerifgfpvhytdvsnmgrgarqkllgrswsvpvirhlfaplkdyface
interface signature	NVPKSN/NVPQKSN

Estimated binding specificities ?

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# IC=7.416 IC/col=0.436 n_of_columns=17

specificity:

A |   5   5   0   5  24  24  24  24  24  24  24  24  24   0   0  79  79
C |   5   5   0   5  24  24  24  24  24  24  24  24  24  91  96   7   5
G |   5   7  96  79  24  24  24  24  24  24  24  24  24   0   0   5   7
T |  81  79   0   7  24  24  24  24  24  24  24  24  24   5   0   5   5

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updated Tue Sep 10 15:21:34 2024