6kdk_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y:DNA:DCTP TERNARY COMPLEX
reference	Hattori et al. 'Sci 10 3021 2020
source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 / HUMAN IMMUNODEFICIENCY VIRUS 1
experiment	X-ray (resolution=2.56, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kdk_C interface=24,61,74,76,78,94,151,157,183,184,265,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpMgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6kdk_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkdstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkGspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIMPYMNQY/EKRLKAGQLYT

Estimated binding specificities ?

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# IC=9.764 IC/col=0.296 n_of_columns=33

specificity:

A |   0   0  24   0  24  13  24  24  24  24  24  24  24  24  24   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  13   0   0
C |   0   0  24  96  24  54  24  24  24  24  24  24  24  24  24   0  24  24   0  24  24  24  24  24  24  24  24  24  24  24  16   0   0
G |   0  96  24   0  24  13  24  24  24  24  24  24  24  24  24   0  24  24  96  24  24  24  24  24  24  24  24  24  24  24  54  96  96
T |  96   0  24   0  24  16  24  24  24  24  24  24  24  24  24  96  24  24   0  24  24  24  24  24  24  24  24  24  24  24  13   0   0

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updated Tue Jan 6 06:33:39 2026