6kdm_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y:DNA:ENTECAVIR 5'- TRIPHOSPHATE TERNARY COMPLEX
reference	Hattori et al. 'Sci 10 3021 2020
source	HUMAN IMMUNODEFICIENCY VIRUS 1 / HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.32, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kdm_C interface=24,61,63,74,76,78,94,157,183,184,265,448,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6kdm_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkDstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFILDRIPYMNRQY/EKDRLKAQLYT

Estimated binding specificities ?

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# IC=10.528 IC/col=0.319 n_of_columns=33

specificity:

A |   0   0   7   0  24  11  24  24  24  24  24  24  24  24  24   3  24   0   3  24  24  24  24  24  24  24  24  24  24  24   3   0   3
C |   0  96   8  96  24  60  24  24  24  24  24  24  24  24  24  13  24   0   3  24  24  24  24  24  24  24  24  24  24  24   6   0  79
G |   0   0  70   0  24  14  24  24  24  24  24  24  24  24  24   7  24   0  84  24  24  24  24  24  24  24  24  24  24  24  84  96  11
T |  96   0  11   0  24  11  24  24  24  24  24  24  24  24  24  73  24  96   6  24  24  24  24  24  24  24  24  24  24  24   3   0   3

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updated Tue Jan 6 06:34:27 2026