6kdo_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y/M184V/F160M:DNA:LAMIVUDINE 5'-TRIPHOSPHATE TERNARY COMPLEX
reference	Hattori et al. 'Sci 10 3021 2020
source	HUMAN IMMUNODEFICIENCY VIRUS 1 / HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
experiment	X-ray (resolution=2.57, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6kdo_C interface=23,60,73,75,77,93,150,156,182,264,474,500, ispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpMgwkgsPaimqssmtkilepfrkqnpdiviyqYvddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 6kdo_D interface= ietvpvklkpgmdgpkvkqwplTeekikalveictemekegkiskigpenpyntpvfaiKkkdstkwrklvdFrElNkrtqdfwevqlgiphPaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwKgspaiFqssmtkilepfrkqnpdiviyqymdDlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrGtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFLDRIMPYNQY/TKFENPKFDG

Estimated binding specificities ?

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# IC=7.965 IC/col=0.249 n_of_columns=32

specificity:

A |   0   0  24   0  24   9  24  24  24  24  24  24  24  24  24   0  24  24  11  24  24  24  24  24  24  24  24  24  24  24   9   0
C |   0   0  24  96  24  67  24  24  24  24  24  24  24  24  24   0  24  24   9  24  24  24  24  24  24  24  24  24  24  24  11   0
G |   0  96  24   0  24  11  24  24  24  24  24  24  24  24  24   0  24  24  67  24  24  24  24  24  24  24  24  24  24  24  67  96
T |  96   0  24   0  24   9  24  24  24  24  24  24  24  24  24  96  24  24   9  24  24  24  24  24  24  24  24  24  24  24   9   0

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updated Tue Jan 6 06:36:43 2026