6ldi_CDFGH : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'beta and beta-prime subunits of DNA dependent RNA-polymerases', as these often contain single-stranded DNA molecules which accumulate many base contacts which distort the calculations.

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updated Sat Dec 14 15:48:00 2024

structure name	THE CRYO-EM STRUCTURE OF E. COLI CUER TRANSCRIPTION ACTIVATION COMPLEX
source	ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experiment	NMR
structural superfamily	cAMP-binding domain-like;"Winged helix" DNA-binding domain;P-loop containing nucleoside triphosphate hydrolases;Putative DNA-binding domain;beta and beta-prime subunits of DNA dependent RNA-polymerase;Nucleic acid-binding proteins;Rho N-terminal domain-like;Probable bacterial effector-binding domain;Homeodomain-like;Insert subdomain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;C-terminal domain of RNA polymerase alpha subunit;lambda repressor-like DNA-binding domains;CheY-like;C-terminal effector domain of the bipartite response regulators;
reference complex	3iyd_H 5nss_G 6ldi_G 6vu3_A 6vz3_A 6xas_B 6xh7_H 6xl5_H 7vwz_G 7w5x_A 8igr_C 8jo2_H 8u3b_G 8upo_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6ldi_C interface=149,181,197,198,199,369,372,443,444,449,494,536,540,545, ysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhRspgvffdsdkgkthssgkvlynariipyrgsWldfefdpkdnlfvriDRRrklpatiilralnytteqildlffekvifeirdnklqmelvperlrgetasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiyrmmRpgEpptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddIDhlgnRrirsvgemaenqfrvglvrveravkerlslgdldtlmpqdminaKpisaavkeffgssqlsqfmdqnnplseithkrrisalgpggLtreRagfeVrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginiele > 6ldi_D interface=303,304,411,774,775, fdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggrfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgSNkrplksladmikgkqgrfrqnllgkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfiygklelrglattikaakkmvereeavvwdildevirehpvllnraPtlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalkTAnsgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqltssiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrr > 6ldi_F interface=4,6,7,10,13,18,24,236,238,239,249,272,273,276,278,281,282,283,285,286,287,290,293,294,308,321,358,362,364,372,375,426,437,438,439,442, rttDpVRmyMreMgtveLltregEidiakriedginqvqcsvaeypeaitylleqydrveaensidpelarekfaelraqyvvtrdtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveaNlRLvisiakkytNrglqfldliqegniglmkavdkFEyrRgYkfSTYaTWWirQaiTRsiadqartiripvHmietinklnrisRqmlqemgreptpeelaermlmpedkirkvlkiakepIsmeTpIgddedshLgdFiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytLeevgkqfdvtRERirQieakalrklrhpsrsevlrsfld > 6ldi_G interface=15,18,19,36, mnisdvakitgltsKaiRFyeekglvtppmrsengYrtytqqhlneltllrqarqvgfnleesgelvnlfndpqrhsadvkrrtlekvaeierhieelqsmrdqllalanacpgddsadcpiienls > 6ldi_H interface=15,18,19,36, mnisdvakitgltsKaiRFyeekglvtppmrsengYrtytqqhlneltllrqarqvgfnleesgelvnlfndpqrhsadvkrrtlekvaeierhieelqsmrdqllalanacpgddsadcpiienlsg