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structure nameDNA BOUND ANTITOXIN HIGA3
(Putative antitoxin HigA3)
referencePark et al. Iucrj 7 748 2020
sourceMycobacterium tuberculosis H37Rv
experimentX-ray (resolution=3.28, R-factor=0.280)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyHelixturnhelix;
multimeric complexes6lty_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSQARSK

Estimated binding specificities ?

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# IC=1.271 IC/col=0.254 n_of_columns=5 specificity:   
A |  13  22  19  67   8
C |  56  27  20   9   8
G |  13  22  38  11  72
T |  14  25  19   9   8
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----SCQCAGRCSCKT----------   L                     +------6lty_B    
                                                +----4 
  --AT--QAAT----SA----------                    !    +------4z5h_A    
                                           +----6 
  QTTTKTQAQASTQALT----TT----   L           !    !           +3cro_R    
                                           !    !     +-----1 
  --ATSTATPT--NT------------               !    +-----2     +6jpi_C    
                                     +-----7          ! 
  --ET----QASG--------------   L     !     !          +-----1lmb_4    
                                     !     ! 
  QA--TAKGKT--IG--------YT--   L     !     !        +-------4pu3_C    
                                   +-8     +--------5 
  ----TTQA--LTSAET----------   L   ! !              +-------2o4a_A    
                                   ! ! 
  --STKCQAAT----SA----------   L --9 !                +-----3dnv_B    
                                   ! +----------------3 
  QT--TTQAQGST--ECQTKC----RA   L   !                  +-----1per_L    
                                   ! 
  --ETDTRGTCYTST------------   L   +------------------------3s8q_A

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updated Fri Sep 13 22:33:44 2024