Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF HUMAN NEIL1(P2G, E3Q, K242) BOUND TO DUPLEX DNA CONTAINING DIHYDROTHYMINE (DHT)
(Endonuclease 8-like 1)
referenceZhang et al. 'Nat 12 4108 2021
sourceHomo sapiens
experimentX-ray (resolution=2.78, R-factor=0.203)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyEndonuclease VIIIlike 1, DNA bind; FormamidopyrimidineDNA glycosylase H2;
reference complex8ftj_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=4.055 IC/col=0.579 n_of_columns=7 specificity:   
A |  19  24  24  24   0   0   0
C |  19  24  24  24  96  96   0
G |  19  24  24  24   0   0   0
T |  39  24  24  24   0   0  96
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updated Fri Sep 13 00:47:39 2024