Estimated binding specificities ?

structure nameCRYSTAL STRUCTURE OF HUMAN NEIL1(P2G, E3Q, R242) BOUND TO DUPLEX DNA CONTAINING DIHYDROTHYMINE (DHT)
(Endonuclease 8-like 1)
referenceZhang et al. 'Nat 12 4108 2021
sourceHomo sapiens
experimentX-ray (resolution=2.72, R-factor=0.207)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyEndonuclease VIIIlike 1, DNA bind; FormamidopyrimidineDNA glycosylase H2;
reference complex8ftj_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
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# IC=4.329 IC/col=0.722 n_of_columns=6 specificity:   
A |  52   7  31   0   0   4
C |  14   7  23  96  96   4
G |  14  75  21   0   0   4
T |  16   7  21   0   0  84
scan!

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updated Fri Sep 13 00:47:41 2024