structure nameCRYSTAL STRUCTURE OF HUMAN NEIL1(R242) BOUND TO DUPLEX DNA CONTAINING A C:T MISMATCH
(Endonuclease 8-like 1)
referenceZhang et al. 'Nat 12 4108 2021
sourceHomo sapiens
experimentX-ray (resolution=2.89, R-factor=0.239)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyEndonuclease VIIIlike 1, DNA bind; FormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2;
reference complex8ftj_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePEMRFYYRHR

Estimated binding specificities ?

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# IC=3.723 IC/col=0.532 n_of_columns=7 specificity:   
A |   9  24  24  24   0   0   7
C |   9  24  24  24  96  96   7
G |   9  24  24  24   0   0   8
T |  69  24  24  24   0   0  74
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updated Fri Sep 13 00:48:09 2024