interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN NEIL1(R242) BOUND TO DUPLEX DNA CONTAINING A C:T MISMATCH
(Endonuclease 8-like 1)
referenceZhang et al. 'Nat 12 4108 2021
sourceHomo sapiens
experimentX-ray (resolution=2.89, R-factor=0.239)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyEndonuclease VIIIlike 1, DNA bind; FormamidopyrimidineDNA glycosylase N; FormamidopyrimidineDNA glycosylase H2;
reference complex8ftj_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePEMRFYYRHR

Estimated binding specificities ?

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# IC=4.118 IC/col=0.588 n_of_columns=7 specificity:   
A |  96   0   0  22  24  24  45
C |   0   0   0  22  24  24  16
G |   0   0  96  22  24  24  19
T |   0  96   0  30  24  24  16
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updated Mon Dec 18 16:41:06 2023