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interface graphfootprint logointerface matrixatomic interactionsinterface residue numbers

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

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updated Mon Dec 18 17:18:32 2023

structure name	HUMAN DNA LIGASE 1 BOUND TO AN ADENYLATED, DIDEOXY TERMINATED DNA NICK WITH 2 MM MG2+ (DNA ligase 1)
reference	Schellenberg et al. 'Nat 10 5431 2019
source	Homo sapiens
experiment	X-ray (resolution=2.05, R-factor=0.172)
structural superfamily	ATP-dependent DNA ligase DNA-binding domain;DNA ligase/mRNA capping enzyme, catalytic domain;Nucleic acid-binding proteins;
sequence family	ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal re;
reference complex	6p0c_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6p0a_A interface=284,373,381,508,509,536,610, sndpsgynpaknnyhpvedacwkpgqkvpylavartfekieevsarlrmvetlsnllrsvvalsppdllpvlylslnhlgppqqglelgvgdgvllkavaqatgrqlesvraeaaekgdvglvaensqrlmlppppltasgvfskfrdiarltgsastakkidiikglfvacrhsearfiarslsgrlrlglaeqsvlaalsqavsltppgqefppamvdagkgktaearktwleeqgmilkqtfcevpdldriipvllehglerlpehcklspgiplkpmlaHptrgisevlkrfeeaaftceykydgqraqihaleggevkifsrnqedntgkypdiisripkiklpsvtsfildteavawdrekkqiqpFqvlttrkRkevdaseiqvqvclyafdliylngeslvreplsrrrqllrenfvetegefvfatsldtkdieqiaefleqsvkdsceglmvktldvdatyeiakrshnwlklkkdyldgvgdtldlvvigaylgrgKRagryggfllasydedseelqaicklgTgfsdeeleehhqslkalvlpsprpyvridgavipdhwldpsavwevkcadlslspiypaarglvdsdkgislrFprfirvredkqpeqattsaqvaclyrkqs