interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HIV CLEAVED SYNAPTIC COMPLEX (CSC) INTASOME BOUND WITH MAGNESIUM AND INSTI XZ426 (COMPOUND 4D)
referenceJozwik et al. Science 367 810 2020
experimentX-ray (resolution=2.80, R-factor=?)
structural superfamilyDNA-binding domain of retroviral integrase;
reference complex6puy_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHQESK/R/

Estimated binding specificities ?

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# IC=3.142 IC/col=0.209 n_of_columns=15 specificity:   
A |  13  24  24  24  24  24  24  24  24  24  24  24  54   0   0
C |  13  24  24  24  24  24  24  24  24  24  24  24  16   0  96
G |  57  24  24  24  24  24  24  24  24  24  24  24  13  96   0
T |  13  24  24  24  24  24  24  24  24  24  24  24  13   0   0
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updated Tue Sep 10 19:00:15 2024