interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HIV CLEAVED SYNAPTIC COMPLEX (CSC) INTASOME BOUND WITH MAGNESIUM AND INSTI XZ426 (COMPOUND 4D)
referenceJozwik et al. Science 367 810 2020
experimentX-ray (resolution=2.80, R-factor=?)
structural superfamilyChromo domain-like;
reference complex1bbx_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHQESK/R/

Estimated binding specificities ?

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# IC=3.101 IC/col=0.207 n_of_columns=15 specificity:   
A |   0   0  16  24  24  24  24  24  24  24  24  24  24  24  13
C |   0  96  13  24  24  24  24  24  24  24  24  24  24  24  54
G |  96   0  13  24  24  24  24  24  24  24  24  24  24  24  13
T |   0   0  54  24  24  24  24  24  24  24  24  24  24  24  16
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updated Thu Jun 25 21:52:06 2026