6pw2_ABCD : 3D-footprint complex

structure name	STRUCTURAL BASIS FOR COOPERATIVE BINDING OF EBNA1 TO THE EPSTEIN-BARR VIRUS DYAD SYMMETRY MINIMAL ORIGIN OF REPLICATION
reference	Lieberman et al. J.Virol. 93 ? 2019
source	Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8)
experiment	X-ray (resolution=3.01, R-factor=?)
structural superfamily	Viral DNA-binding domain;
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6pw2_A interface=1,4,5,9,17,54,55,58,59,62, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_B interface=1,4,5,9,17,54,55,58,59, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_C interface=4,5,9,17,54,55,58,59,62, kggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_D interface=1,4,5,9,17,54,55,58, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYnlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRKKTYNR/KWFRKKTYN/WFRKKTYNR/KWFRKKTY

Estimated binding specificities ?

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# IC=25.119 IC/col=0.698 n_of_columns=36

specificity:

A |  90   0  96   9   1  24  24  24  13  24   0   1  24   0   0   0  24  24  24   0   0   1  24  92   1   3  24  24  24  24  24   3   0  96   1   0
C |   1   0   0   0  92  24  24  24  11  24   0   1  24  89  96  96  24  24  24   0   0   7  24   0   4  80  24  24  24  24  24  92   1   0   1  96
G |   4   0   0  86   1  24  24  24  11  24   0   1  24   0   0   0  24  24  24  96  96  84  24   3  90   9  24  24  24  24  24   1   3   0   1   0
T |   1  96   0   1   2  24  24  24  61  24  96  93  24   7   0   0  24  24  24   0   0   4  24   1   1   4  24  24  24  24  24   0  92   0  93   0

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updated Thu Jul 31 00:07:06 2025