6pw2_ABCD : 3D-footprint complex

structure name	STRUCTURAL BASIS FOR COOPERATIVE BINDING OF EBNA1 TO THE EPSTEIN-BARR VIRUS DYAD SYMMETRY MINIMAL ORIGIN OF REPLICATION
reference	Lieberman et al. J.Virol. 93 ? 2019
source	Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8)
experiment	X-ray (resolution=3.01, R-factor=?)
structural superfamily	Viral DNA-binding domain;
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6pw2_A interface=1,4,5,9,17,54,55,58,59,62, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_B interface=1,4,5,9,17,54,55,58,59, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_C interface=4,5,9,17,54,55,58,59,62, kggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_D interface=1,4,5,9,17,54,55,58, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYnlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRKKTYNR/KWFRKKTYN/WFRKKTYNR/KWFRKKTY

Estimated binding specificities ?

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# IC=24.052 IC/col=0.668 n_of_columns=36

specificity:

A |   0  96   0  90   1  24  24  24  24  24  11   0   0  24  11   0   1  24  24  24   1   0   0  24  92  95  24  74  24  24  24   5   0   0  83   1
C |   0   0   0   4   3  24  24  24  24  24  19  96   0  24  69  96  92  24  24  24   4   0   0  24   3   1  24   3  24  24  24   7  91   0   1   0
G |  96   0   0   1  92  24  24  24  24  24  61   0   0  24   7   0   3  24  24  24  90  96  91  24   0   0  24   8  24  24  24  78   0   0   9   1
T |   0   0  96   1   0  24  24  24  24  24   5   0  96  24   9   0   0  24  24  24   1   0   5  24   1   0  24  11  24  24  24   6   5  96   3  94

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updated Tue Jan 6 11:06:38 2026