6pw2_ABCD : 3D-footprint complex

structure name	STRUCTURAL BASIS FOR COOPERATIVE BINDING OF EBNA1 TO THE EPSTEIN-BARR VIRUS DYAD SYMMETRY MINIMAL ORIGIN OF REPLICATION
reference	Lieberman et al. J.Virol. 93 ? 2019
source	Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8) / Epstein-Barr virus (strain B95-8)
experiment	X-ray (resolution=3.01, R-factor=?)
structural superfamily	Viral DNA-binding domain;
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6pw2_A interface=1,4,5,9,17,54,55,58,59,62, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_B interface=1,4,5,9,17,54,55,58,59, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_C interface=4,5,9,17,54,55,58,59,62, kggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp > 6pw2_D interface=1,4,5,9,17,54,55,58, KggWFgkhRgqggsnpKfeniaeglrallarshverttdegtwvagvfvyggsKTslYnlrrgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRKKTYNR/KWFRKKTYN/WFRKKTYNR/KWFRKKTY

Estimated binding specificities ?

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# IC=24.941 IC/col=0.693 n_of_columns=36

specificity:

A |  96   1  96  11   1  24  24  24   8  24   0   0  24   3   0   0  24  24  24   0   0   9  24  90   0  32  24  24  24  24  24   1   0  96   1   0
C |   0   0   0   6  91  24  24  24   7  24   0   0  24  84  96  96  24  24  24   0   0   3  24   3   0  42  24  24  24  24  24  92   0   0   1  96
G |   0   0   0  76   3  24  24  24   3  24   0   0  24   0   0   0  24  24  24  96  96  78  24   2  96  11  24  24  24  24  24   3   0   0   0   0
T |   0  95   0   3   1  24  24  24  78  24  96  96  24   9   0   0  24  24  24   0   0   6  24   1   0  11  24  24  24  24  24   0  96   0  94   0

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updated Thu Jun 25 21:52:40 2026