interface graph thumbnail
legend  pdf

structure nameKLENTAQ DNA POL IN A CLOSED TERNARY COMPLEX WITH 7-DEAZA-7-(2-(2- HYDROXYETHOXY)-N-(PROP-2-YN-1-YL)ACETAMIDE)-2-DATP
(DNA polymerase I, thermostable)
referenceDiederichs et al. Angew.Chem.Int.Ed.Engl. 58 5457 2019
sourceThermus aquaticus
experimentX-ray (resolution=2.00, R-factor=0.187)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTYRNNENQH

Estimated binding specificities ?

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# IC=0.457 IC/col=0.114 n_of_columns=4 specificity:   
A |  19  16  13  38
C |  20  45  56  19
G |  38  19  14  20
T |  19  16  13  19
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updated Fri Jan 9 09:26:32 2026