interface graph thumbnail
legend  pdf

structure nameTHE CRYSTAL STRUCTURE OF POL2CORE IN COMPLEX WITH DNA AND AN INCOMING NUCLEOTIDE, CARRYING AN FE-S CLUSTER
(DNA polymerase epsilon catalytic subunit A)
referenceJohansson et al. 'Nucleic 47 5712 2019
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.80, R-factor=0.227)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B, exonuclease do; DNA polymerase family B 897;
reference complex4m8o_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQKRR

Estimated binding specificities ?

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# IC=2.681 IC/col=0.670 n_of_columns=4 specificity:   
A |  88  81  22   7
C |   1   7  53   7
G |   0   7  14  75
T |   7   1   7   7
scan!

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updated Sat Aug 2 13:40:03 2025