interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF MUTM FROM NEISSERIA MENINGITIDIS
(Formamidopyrimidine-DNA glycosylase)
referenceLandova et al. 'Febs 594 3032 2020
sourceNeisseria meningitidis alpha522
experimentX-ray (resolution=2.17, R-factor=0.240)
structural superfamilyN-terminal domain of MutM-like DNA repair proteins;S13-like H2TH domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyFormamidopyrimidineDNA glycosylase H2; FormamidopyrimidineDNA glycosylase N;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRMRFR

Estimated binding specificities ?

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# IC=3.022 IC/col=0.604 n_of_columns=5 specificity:   
A |  19  60   0  24   0
C |  19  12  96  24   0
G |  38  12   0  24   0
T |  20  12   0  24  96
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT--MG----RCFC--------RT   L                          +--6tc9_A    
                                                      +-1 
  RA--MG----RCFCKGDGACQTRG   L               +--------2 +--1k82_A    
                                             !        ! 
  --RA------RGFT--------RA   L   +-----------3        +--3gpu_A    
                                 !           ! 
  --QALGYA--------------RG     --4           +-----------1k3x_A    
                                 ! 
  ----LG--MTRCFC--------RT   L   +-----------------------3vk8_B

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updated Tue Dec 19 14:55:28 2023