interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE GGCT SITE-BOUND MH1 DOMAIN OF SMAD5 CONTAINING A GGGS INSERTION IN THE LOOP1
(Mothers against decapentaplegic homolog 5)
referenceMacias et al. 'Comput 19 632 2021
sourceHomo sapiens
experimentX-ray (resolution=2.92, R-factor=0.210)
structural superfamilySMAD MH1 domain;
sequence familyMH1 domain;
multimeric complexes3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB 6fzt_AB
reference complex6fzs_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDRQK

Estimated binding specificities ?

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# IC=3.184 IC/col=0.796 n_of_columns=4 specificity:   
A |  13  96   0  13
C |  13   0   0  57
G |  13   0  96  13
T |  57   0   0  13
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updated Sat Aug 2 14:17:46 2025